Oliver Freudenreich, M.D.

When should you taper a benzodiazepine, and how slowly? Does semaglutide reverse metabolic risk in schizophrenia patients on clozapine or olanzapine? Is EPA effective for TRD? Can brief psychotherapy enable safe antidepressant discontinuation? Is a ketogenic diet effective for depression and other psychiatric conditions?

When should you consider high-dose olanzapine instead of clozapine for treatment-resistant schizophrenia? How effective is aripiprazole augmentation versus switching strategies in older adults with depression? Can GLP-1 receptor agonists elevate lithium levels? Should inflammatory markers guide antidepressant selection? Is adjunctive propranolol effective for panic disorder?

What are the six key tips for switching oral antipsychotics? Does deprescribing antipsychotics after delirium improve outcomes in older adults? Why is xylazine overdose difficult to treat? What does the PAX-D study reveal about pramipexole for depression? Do bioequivalent medications always produce equivalent clinical results?

Can ondansetron improve negative symptoms in schizophrenia? Will lithium orotate prevent or reverse Alzheimer's disease? What predicts treatment response in bipolar disorder? Should we increase SSRI doses or try alternative strategies for inadequate response? Is trazodone safe for treating insomnia in alcohol use disorder?

How effective is the new antipsychotic KarXT using the number needed to treat metric? Can bright light therapy effectively treat bipolar depression without causing mania? Does IV haloperidol really increase cardiac risks as commonly believed? Can varenicline help reduce alcohol intake in people with alcohol use disorder? Does ashwagandha extract improve cognitive function in mild cognitive impairment?

How should clozapine monitoring change after FDA's REMS removal? Does cariprazine work equally well in older adults with bipolar disorder? Can semaglutide help treat alcohol use disorder? Why do older adults receive subtherapeutic antidepressant doses? Is saffron as effective as SSRIs for depression?

Can pramipexole help treatment-resistant bipolar depression? Does semaglutide work for clozapine-induced obesity? Which antipsychotics best prevent hospitalization after cannabis-induced psychosis? What treatments rank highest for treatment-resistant depression? How do gut microbiota differ in depression versus anxiety disorders?

What is the best antipsychotic for first-episode psychosis? Can lurasidone treat bipolar depression with severe anxiety? How much do SSRIs increase bleeding when combined with anticoagulants? Is adding salt to meals associated with depression and anxiety?